Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 12/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657345 | 0.84 | ESR1 (0.53) | STSESR1ESR2NR3C1LMNA | |
| SCHEMBL2401211 | 0.83 | ESR1 (0.53) | STSESR1ESR2NR3C1LMNA | |
| SCHEMBL4645148 | 0.80 | ESR1 (0.63) | STSESR1ESR2NR3C1LMNA | |
| SCHEMBL1656677 | 0.80 | ESR1 (0.63) | STSESR1ESR2NR3C1LMNA | |
| SCHEMBL8151660 | 0.79 | ESR1 (0.52) | STSESR1ESR2NR3C1LMNA | |
| SCHEMBL11688794 | 0.79 | ESR1 (0.70) | STSESR1ESR2NR3C1LMNA | |
| SCHEMBL4572560 | 0.79 | STS (0.73) | STSESR1ESR2NR3C1PGR | |
| SCHEMBL7166132 | 0.79 | STS (0.73) | STSESR1ESR2NR3C1PGR | |
| SCHEMBL1656550 | 0.79 | STS (0.73) | STSESR1ESR2NR3C1PGR | |
| SCHEMBL8151691 | 0.78 | ESR1 (0.53) | STSESR1ESR2NR3C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998032763-A1 | STEROID INHIBITORS OF ESTRONE SULFATASE, AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SRI INTERNATIONAL (US) | 1998-07-30 | — | — | WO | disclosed |