Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.63 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075228 | 0.89 | AKR1C2 (0.74) | KMT2AMEN1TSHRAKR1C2AKR1C1 | |
| SCHEMBL882567 | 0.86 | MEN1 (0.76) | KMT2AMEN1TSHRNPC1RAB9A | |
| SCHEMBL23657660 | 0.86 | RAB9A (0.78) | KMT2AMEN1TSHRNPC1RAB9A | |
| SCHEMBL26117333 | 0.83 | NPC1 (0.62) | KMT2AMEN1TSHRNPC1RAB9A | |
| SCHEMBL6720875 | 0.82 | MEN1 (0.73) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL8639160 | 0.81 | NPC1 (0.60) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL27248654 | 0.80 | LMNA (0.57) | KMT2AMEN1TSHRAKR1C2AKR1C1 | |
| SCHEMBL29578689 | 0.79 | NPC1 (0.64) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL24489100 | 0.79 | NPC1 (0.64) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL26388870 | 0.78 | MEN1 (0.62) | KMT2AMEN1AKR1C2AKR1C1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |