Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639573 | 0.88 | RAB9A (0.70) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL8643674 | 0.86 | KMT2A (0.69) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL8638433 | 0.81 | KMT2A (0.63) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL8639241 | 0.80 | KDM4E (0.60) | RAB9AKDM4ESMN1; SMN2MAPK10MEN1 | |
| SCHEMBL8638900 | 0.80 | MAPK8 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL3628197 | 0.78 | SIRT2 (0.70) | KDM4ESMN1; SMN2MAPK10KMT2ASIRT2 | |
| SCHEMBL4010528 | 0.77 | TP53 (0.51) | KDM4ESMN1; SMN2TP53RECQLPKM | |
| SCHEMBL8638566 | 0.77 | SMN1; SMN2 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL8638570 | 0.77 | SMN1; SMN2 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL19062092 | 0.76 | SMN1; SMN2 (0.65) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |