Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367182 | 0.88 | CHEK1 (0.80) | LMNACHEK1PIM1MAPK8CLK4 | |
| SCHEMBL4699872 | 0.88 | CHEK1 (0.76) | L3MBTL1LMNACHEK1PIM1MAPK8 | |
| SCHEMBL8635556 | 0.83 | KDM4E (0.77) | CHEK1PIM1MAPK8CLK4ALDH1A1 | |
| SCHEMBL8638027 | 0.82 | MEN1 (0.67) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22340657 | 0.81 | TSHR (0.75) | LMNASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL4523815 | 0.81 | MAPK9 (0.76) | LMNACHEK1PIM1MAPK8CLK4 | |
| SCHEMBL24489009 | 0.81 | KMT2A (0.80) | LMNACHEK1PIM1MAPK8CLK4 | |
| SCHEMBL29579206 | 0.81 | KMT2A (0.80) | LMNACHEK1PIM1MAPK8CLK4 | |
| SCHEMBL14256345 | 0.80 | L3MBTL1 (0.58) | L3MBTL1LMNACHEK1PIM1MAPK8 | |
| SCHEMBL8641094 | 0.80 | KMT2A (0.57) | LMNAALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225745-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | Athenex, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076662-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | ATHENEX, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |