Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999390 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL20419616 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL3068995 | 0.84 | HSP90AA1 (0.50) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL3068994 | 0.84 | HSP90AA1 (0.50) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL15516659 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL18059374 | 0.80 | LMNA (0.49) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL18290561 | 0.79 | MEN1 (0.49) | ALDH1A1MAPTKMT2AHPGDRAB9A | |
| SCHEMBL20419668 | 0.79 | KMT2A (0.39) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL20419661 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AHSP90AA1HPGD | |
| SCHEMBL14344759 | 0.79 | ATM (0.41) | ALDH1A1MAPTKMT2AHSP90AA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622381-B1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORP (JP) | 1998-07-29 | — | — | EP | claimed |
| EP-0451603-B1 | Elastomers and products having reduced hysteresis | BRIDGESTONE FIRESTONE INC (US) | 1996-02-07 | — | — | EP | claimed |
| EP-0622381-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-11-02 | — | — | EP | claimed |
| US-5354822-A | Endcapping the addition polymerization with a reaction product of an aldimines, a ketimines, a secondary amines and an organo lithium compound prior quenching | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-10-11 | — | — | US | claimed |
| US-5268413-A | Blend of functionalized polymer and organolithium compound | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-12-07 | — | — | US | claimed |
| US-5153159-A | ELASTOMERS AND PRODUCTS HAVING REDUCED HYSTERESIS | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | claimed |
| EP-0451603-A2 | Elastomers and products having reduced hysteresis | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | claimed |
| EP-0622381-B1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORP (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-5698646-A | ANIONIC POLYMERIZATION OF BUTADIENE-STYRENE COPOLYMER USING LITHIUM COMPOUND AND CHELATE COMPOUND | BRIDGESTONE CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0510410-B1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE FIRESTONE INC (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0451603-B1 | Elastomers and products having reduced hysteresis | BRIDGESTONE FIRESTONE INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0639587-A1 | Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE/FIRESTONE, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5227431-A | DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0510410-A1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5153159-A | ELASTOMERS AND PRODUCTS HAVING REDUCED HYSTERESIS | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5109907-A | Tire treads with reduced rolling resistance | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5066729-A | Tire Treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0451603-A2 | Elastomers and products having reduced hysteresis | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0451604-A2 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |