SCHEMBL18059374

SCHEMBL18059374

C/N=C(/c1ccccc1)N(C)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
FAAH O00519 1/20 0.44
PHGDH O43175 1/20 0.44
MGLL Q99685 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
KMT2A Q03164 4/20 0.42
HTT P42858 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
GFER P55789 1/20 0.40
MAPT P10636 2/20 0.39
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11847946 0.86 KMT2A (0.43) LMNAL3MBTL1KMT2AALDH1A1HPGD
SCHEMBL11341984 0.81 KMT2A (0.48) LMNAL3MBTL1KMT2AHTTALDH1A1
SCHEMBL25452700 0.81 KMT2A (0.48) LMNAL3MBTL1KMT2AHTTALDH1A1
SCHEMBL8638472 0.80 ALDH1A1 (0.48) KMT2AKDM4EALDH1A1HPGDGFER
SCHEMBL20419616 0.80 ALDH1A1 (0.48) KMT2AKDM4EALDH1A1HPGDGFER
SCHEMBL14999390 0.80 ALDH1A1 (0.48) KMT2AKDM4EALDH1A1HPGDGFER
SCHEMBL3068995 0.78 HSP90AA1 (0.50) KMT2AKDM4EALDH1A1HPGDGFER
SCHEMBL3068994 0.78 HSP90AA1 (0.50) KMT2AKDM4EALDH1A1HPGDGFER
SCHEMBL20419693 0.77 KMT2A (0.38) LMNAKMT2AHTTKDM4EALDH1A1
SCHEMBL18597559 0.77 KMT2A (0.48) LMNAFAAHPHGDHMGLLCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11545637-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-03 US disclosed
US-20180212163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-26 US disclosed
US-20160260909-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG LMNA 4114/4885FAAH 2538/4885PHGDH 3087/4885
US-11545637-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG LMNA 4114/4885FAAH 2538/4885PHGDH 3087/4885
US-20160260909-A1 Organic Electroluminescent Materials and Devices PNMT, CYCS, NES LMNA 2892/4885FAAH 4368/4885PHGDH 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.