Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639409 | 0.88 | BCHE (0.43) | BCHENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9132314 | 0.87 | BCHE (0.44) | BCHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8636531 | 0.86 | BCHE (0.53) | BCHENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8638250 | 0.84 | SCN9A (0.50) | BCHENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9135007 | 0.83 | BCHE (0.52) | BCHENPC1RAB9ASMN1; SMN2SLC2A1 | |
| SCHEMBL8638563 | 0.82 | MEN1 (0.49) | BCHEMEN1KMT2ASLC2A1FFAR1 | |
| SCHEMBL8635189 | 0.81 | KCNH2 (0.43) | BCHEMEN1KMT2A | |
| SCHEMBL8636498 | 0.81 | FAAH (0.42) | BCHE | |
| SCHEMBL8638572 | 0.80 | SCN9A (0.57) | SCN9A | |
| SCHEMBL9134138 | 0.80 | ADRB2 (0.39) | BCHENPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643688-B1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| US-5446066-A | Antiepileptic, antidepressants, antispastic agent | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-08-29 | — | — | US | disclosed |