Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628018 | 0.83 | EPHX1 (0.57) | EPHX1ACHETSHRHTTPLA2G4A | |
| SCHEMBL8641908 | 0.82 | HDAC3 (0.52) | ACHEHTTKMT2AHDAC3HDAC4 | |
| SCHEMBL24327111 | 0.81 | MEN1 (0.60) | EPHX1HTTGAAMEN1KMT2A | |
| SCHEMBL7252127 | 0.79 | EPHX1 (0.77) | EPHX1ACHETSHRMEN1KMT2A | |
| SCHEMBL14433357 | 0.79 | EPHX1 (0.70) | EPHX1ACHETSHRGAAMEN1 | |
| SCHEMBL7769326 | 0.78 | EPHX1 (0.57) | EPHX1ACHETSHRHTTGAA | |
| SCHEMBL21538522 | 0.78 | TSHR (0.61) | EPHX1ACHETSHRCA12ALDH1A1 | |
| SCHEMBL12972297 | 0.78 | EPHX1 (0.57) | EPHX1ACHETSHRADRA1AALDH1A1 | |
| SCHEMBL7788927 | 0.77 | EPHX1 (0.82) | EPHX1ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL14252129 | 0.77 | EPHX1 (0.82) | EPHX1ACHEMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756822-A | ANTIULCER | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5672597-A | ANTIULCER AGENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0673925-A1 | ACETAMIDE DERIVATIVE | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |