Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379990 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL11230429 | 0.72 | MAPT (0.40) | GABRA1GABRB2NLRP3TSHRHPGD | |
| SCHEMBL30884216 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL5531971 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| Hydrochloric Acid SCHEMBL28248937 | 0.70 | GABRA1 (0.46) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| Hydrochloric Acid SCHEMBL2154213 | 0.70 | GABRA1 (0.46) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL29204723 | 0.69 | GABRA1 (0.44) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL7941340 | 0.68 | GABRA1 (0.40) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL254754 | 0.67 | ALDH1A1 (0.54) | LMNACYP1A2CYP3A4 | |
| SCHEMBL4462607 | 0.67 | TRPA1 (0.35) | NLRP3TSHRCA1CA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | claimed |
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | disclosed |