Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192302 | 0.93 | MAPT (0.39) | MAPTALDH1A1TSHRTHRATHRB | |
| SCHEMBL8641665 | 0.93 | MAPT (0.47) | MAPTALDH1A1TSHRTHRATHRB | |
| SCHEMBL14192318 | 0.81 | THRA (0.36) | MAPTALDH1A1TSHRTHRATHRB | |
| SCHEMBL14192308 | 0.80 | PKM (0.40) | MAPTALDH1A1TSHRTHRATHRB | |
| SCHEMBL19844277 | 0.77 | TLR4 (0.35) | MAPTALDH1A1TSHRTHRATHRB | |
| SCHEMBL14192486 | 0.77 | CYP2C9 (0.59) | MAPTALDH1A1CYP2C9LMNAMAPK1 | |
| SCHEMBL13401006 | 0.75 | TSHR (0.61) | MAPTALDH1A1TSHRTHRBCYP2C9 | |
| SCHEMBL5848308 | 0.74 | THRA (0.68) | MAPTALDH1A1TSHRTHRATHRB | |
| SCHEMBL9759598 | 0.74 | THRA (0.68) | MAPTALDH1A1TSHRTHRATHRB | |
| SCHEMBL182308 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |