Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141077 | 0.88 | EPHX1 (0.38) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL8643093 | 0.75 | ALDH1A1 (0.39) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL8147103 | 0.75 | EPHX1 (0.42) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL8642185 | 0.71 | — | — | |
| SCHEMBL8642674 | 0.71 | — | — | |
| SCHEMBL8146933 | 0.69 | ALDH1A1 (0.38) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL5680415 | 0.67 | TRPM8 (0.47) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL8645771 | 0.66 | METAP1 (0.33) | — | |
| SCHEMBL8155031 | 0.66 | FDPS (0.30) | — | |
| SCHEMBL8152948 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |