SCHEMBL8639154

SCHEMBL8639154

COC(OC)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
CYP1A2 P05177 1/20 0.56
PTGS1 P23219 1/20 0.56
SLC6A2 P23975 1/20 0.56
CYP2C19 P33261 1/20 0.56
PTGS2 P35354 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HIF1A Q16665 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
MAOB P27338 4/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
MAOA P21397 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
BCHE P06276 1/20 0.51
ALOX5 P09917 1/20 0.51
FFAR1 O14842 1/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547764 0.84 LMNA (0.55) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6204244 0.83 LMNA (0.58) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6204242 0.83 LMNA (0.53) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL683554 0.81 RXRA (0.66) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6203969 0.81 MAOB (0.63) LMNAMAOBSMN1; SMN2MAOABCHE
SCHEMBL824976 0.81 LMNA (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL28409723 0.81 LMNA (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL824953 0.81 LMNA (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL2032112 0.81 LMNA (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL11257314 0.80 ALOX5 (0.50) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4284825-A INTERMEDIATES FOR PERFUMES, CROP PROTECTION AGENTS BASF AKTIENGESELLSCHAFT (DE) 1981-08-18 US claimed
EP-0011712-A2 Preparation of benzaldehyde dialkyl acetals substituted in the 4-position BASF Aktiengesellschaft (DE) 1980-06-11 EP claimed
EP-0510449-B1 Acid-cleavable compounds, positive-working radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom CLARIANT GMBH (DE) 1998-08-05 EP disclosed
US-5286602-A Acid-cleavable compounds, positive-working radiation-sensitive mixture containing these compounds, and radiation-sensitive recording material produced with this mixture HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-15 US disclosed
EP-0393667-B1 PROCESS FOR THE PRODUCTION OF BENZYL METHYL ESTERS BASF Aktiengesellschaft (DE) 1993-06-23 EP disclosed
EP-0510449-A2 Acid-cleavable compounds, positive-working radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-28 EP disclosed
EP-0393667-A1 Process for the production of benzyl methyl esters BASF Aktiengesellschaft (DE) 1990-10-24 EP disclosed
US-4457810-A ANODIC OXIDATION OF DI-P-TOLYL ETHER IN PRESENCE OF METHANOL HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-03 US disclosed
EP-0054698-B1 4,4'-DIPHENYL ETHER-DIALDEHYDE-BIS-DIMETHYL ACETAL, AND A METHOD FOR ITS PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-20 EP disclosed
EP-0059373-B1 PROCESS FOR THE PREPARATION OF BENZYL ALCOHOLS BASF Aktiengesellschaft (DE) 1984-05-23 EP disclosed
EP-0054699-B1 METHOD FOR THE CATALYTIC HYDROGENOLYSIS OF PARA-SUBSTITUTED BENZALDEHYDE-DIMETHYL ACETALS INTO THE CORRESPONDING BENZYLMETHYL ETHERS HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-14 EP disclosed
EP-0011712-B1 PREPARATION OF BENZALDEHYDE DIALKYL ACETALS SUBSTITUTED IN THE 4-POSITION BASF Aktiengesellschaft (DE) 1983-06-15 EP disclosed
EP-0059373-A1 Process for the preparation of benzyl alcohols BASF Aktiengesellschaft (DE) 1982-09-08 EP disclosed
EP-0054698-A1 4,4'-Diphenyl ether-dialdehyde-bis-dimethyl acetal, and a method for its preparation HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-30 EP disclosed
EP-0054699-A2 Method for the catalytic hydrogenolysis of para-substituted benzaldehyde-dimethyl acetals into the corresponding benzylmethyl ethers HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-30 EP disclosed
US-4318783-A Process for the preparation of optionally substituted benzaldehyde dialkyl acetals BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
EP-0012240-B1 PROCESS FOR MANUFACTURING OF OPTIONALLY SUBSTITUTED BENZALDEHYD-DIALKYL ACETALS BAYER AG (DE) 1982-01-20 EP disclosed
US-4284825-A INTERMEDIATES FOR PERFUMES, CROP PROTECTION AGENTS BASF AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
EP-0012240-A2 Process for manufacturing of optionally substituted benzaldehyd-dialkyl acetals BAYER AG (DE) 1980-06-25 EP disclosed
EP-0011712-A2 Preparation of benzaldehyde dialkyl acetals substituted in the 4-position BASF Aktiengesellschaft (DE) 1980-06-11 EP disclosed