Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.69 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638900 | 0.90 | MAPK8 (0.65) | RAB9ASMN1; SMN2NPC1TP53KDM4E | |
| SCHEMBL8639160 | 0.88 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1TP53KDM4E | |
| SCHEMBL28642513 | 0.84 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1TP53KDM4E | |
| SCHEMBL30311719 | 0.84 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1TP53KDM4E | |
| SCHEMBL7850198 | 0.84 | POLB (0.73) | POLBKCNQ2GAAUSP2PARP14 | |
| SCHEMBL8637152 | 0.83 | GAA (0.64) | RAB9ASMN1; SMN2KDM4EPOLBGAA | |
| SCHEMBL19061903 | 0.83 | POLB (0.71) | RAB9ASMN1; SMN2RECQLPOLBMAPK8 | |
| SCHEMBL31239012 | 0.82 | NPC1 (1.00) | RAB9ASMN1; SMN2NPC1TP53KDM4E | |
| SCHEMBL26101550 | 0.81 | POLB (0.58) | RAB9ASMN1; SMN2POLBMAPK8KCNQ2 | |
| SCHEMBL30493689 | 0.81 | POLB (0.58) | RAB9ASMN1; SMN2POLBMAPK8KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |