Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070483 | 1.00 | DNM1 (0.38) | DNM1CDC25ATDP1MEN1KMT2A | |
| SCHEMBL15285876 | 0.98 | LTA4H (0.36) | DNM1CDC25ATDP1MEN1KMT2A | |
| SCHEMBL9619306 | 0.92 | LTA4H (0.35) | CDC25ATDP1SMN1; SMN2CES2CES1 | |
| SCHEMBL9619418 | 0.83 | CYP3A4 (0.38) | TDP1TP53 | |
| SCHEMBL8029797 | 0.83 | CYP3A4 (0.41) | TDP1 | |
| SCHEMBL4416335 | 0.79 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL15659895 | 0.79 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL49664 | 0.79 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL6288656 | 0.79 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL6288234 | 0.79 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725072-A1 | Process for the preparation of arylphosphinic acid alkylesters | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-07 | — | — | EP | claimed |
| US-4990674-A | Synthesis of aliphatic aromatic phosphine oxides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-05 | — | — | US | claimed |
| CN-117603264-A | Preparation method of octyl (phenyl) -N, N-diisobutylcarbamoyl methyl phosphine oxide | 浙江扬帆新材料股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| US-5705669-A | DEHYDROHALOGENATION A HALOPHOSPHINE, REACTION WITH ALCOHOL AND NEUTRALIZATION WITH ALCOHOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
| EP-0725072-A1 | Process for the preparation of arylphosphinic acid alkylesters | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-07 | — | — | EP | disclosed |
| US-4990674-A | Synthesis of aliphatic aromatic phosphine oxides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |