Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639965 | 0.86 | SMN1; SMN2 (0.60) | ALDH1A1GAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27752376 | 0.80 | KDM4E (0.54) | ALDH1A1GAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8636692 | 0.79 | KDM4E (0.56) | ALDH1A1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL30621148 | 0.78 | TP53 (0.61) | ALDH1A1KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL8049390 | 0.76 | ALDH1A1 (0.77) | ALDH1A1GAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11870023 | 0.76 | KMT2A (0.60) | ALDH1A1GAAKMT2ASMN1; SMN2PKM | |
| SCHEMBL20183040 | 0.76 | KMT2A (0.60) | ALDH1A1GAAKMT2ASMN1; SMN2PKM | |
| SCHEMBL20183041 | 0.76 | KMT2A (0.60) | ALDH1A1GAAKMT2ASMN1; SMN2PKM | |
| SCHEMBL9386712 | 0.75 | ALDH1A1 (0.59) | ALDH1A1GAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10915384 | 0.75 | KDM4E (0.51) | ALDH1A1KMT2ASMN1; SMN2MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |