Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5176882 | 0.87 | KMT2A (0.52) | KDM4EALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL14577684 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1LMNAMAPK14HPGD | |
| SCHEMBL27752376 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1LMNAMAPK14HPGD | |
| SCHEMBL1715351 | 0.81 | PTGS2 (0.46) | KDM4EALDH1A1LMNAHPGDPOLB | |
| SCHEMBL8639236 | 0.79 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL4819698 | 0.78 | CYP1A2 (0.58) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL13114815 | 0.77 | TSHR (0.64) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL30621148 | 0.77 | TP53 (0.61) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL1409830 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL5365142 | 0.75 | KDM4E (0.65) | KDM4EALDH1A1LMNAMAPK14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |