Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639236 | 0.86 | ALDH1A1 (0.65) | SMN1; SMN2KDM4ERECQLKMT2AMEN1 | |
| SCHEMBL10340325 | 0.80 | TDP1 (0.47) | NPC1RAB9AALDH1A1 | |
| SCHEMBL10340257 | 0.79 | MEN1 (0.50) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL882567 | 0.77 | MEN1 (0.76) | SMN1; SMN2KDM4ENPC1TP53RAB9A | |
| SCHEMBL29543522 | 0.77 | L3MBTL1 (0.63) | ALDH1A1L3MBTL1 | |
| SCHEMBL10340149 | 0.77 | MEN1 (0.47) | SMN1; SMN2KDM4EKMT2AMEN1LMNA | |
| SCHEMBL31239012 | 0.75 | NPC1 (1.00) | SMN1; SMN2KDM4ENPC1TP53RAB9A | |
| SCHEMBL8639573 | 0.75 | RAB9A (0.70) | SMN1; SMN2KDM4ENPC1TP53RAB9A | |
| SCHEMBL28357281 | 0.74 | SIRT2 (0.75) | SMN1; SMN2KDM4ENPC1TP53RAB9A | |
| SCHEMBL1145682 | 0.72 | L3MBTL1 (0.56) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |