Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.59 |
| ▸ | CCKAR | P32238 | 8/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547144 | 0.82 | CCKBR (0.60) | CCKBR | |
| SCHEMBL7041976 | 0.80 | CCKBR (0.50) | CCKBRCCKARSLC6A2MEN1KMT2A | |
| SCHEMBL4424441 | 0.80 | GAA (0.46) | SLC6A2MEN1KMT2A | |
| SCHEMBL8897693 | 0.77 | CCKBR (0.60) | CCKBRCCKARSLC6A2MEN1KMT2A | |
| SCHEMBL4413460 | 0.77 | ALDH1A1 (0.51) | CCKBR | |
| SCHEMBL8543405 | 0.76 | CCKBR (0.60) | CCKBRCCKARSLC6A2 | |
| SCHEMBL8636840 | 0.76 | CCKBR (0.59) | CCKBRCCKARSLC6A2KMT2A | |
| SCHEMBL7041975 | 0.76 | CCKBR (0.42) | CCKBRSLC6A2MEN1KMT2A | |
| SCHEMBL8898463 | 0.76 | CCKBR (0.50) | CCKBRMEN1KMT2A | |
| SCHEMBL8638401 | 0.76 | CCKBR (0.59) | CCKBRCCKARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558104-B1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO WELLCOME SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| US-5637697-A | ANTAGONIST TO GASTRIN AND(OR) CHLOROCYSTOKININ | GLAXO SPA (IT) | 1997-06-10 | — | — | US | disclosed |
| US-5580895-A | GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO SPA (IT) | 1996-12-03 | — | — | US | disclosed |
| EP-0558104-A1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO S.p.A. (IT) | 1993-09-01 | — | — | EP | disclosed |