Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639234 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8145643 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8642476 | 0.76 | ALDH1A1 (0.34) | ALDH1A1LMNASLC6A2SMN1; SMN2 | |
| SCHEMBL8146811 | 0.73 | TRPA1 (0.38) | ALDH1A1TRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL8139371 | 0.73 | ALDH1A1 (0.34) | ALDH1A1KDM4ETDP1NPBWR1SMN1; SMN2 | |
| SCHEMBL8147911 | 0.72 | TRPA1 (0.37) | ALDH1A1TRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL8639156 | 0.69 | TRPA1 (0.40) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8645772 | 0.68 | TRPA1 (0.36) | TRPA1LMNA | |
| SCHEMBL8147939 | 0.68 | TRPA1 (0.38) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8147907 | 0.67 | TRPA1 (0.34) | ALDH1A1TRPA1LMNACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |