Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639375 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8639234 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8639156 | 0.82 | TRPA1 (0.40) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8147939 | 0.74 | TRPA1 (0.38) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8140633 | 0.73 | TRPA1 (0.37) | ALDH1A1KDM4ETDP1TRPA1LMNA | |
| SCHEMBL8139371 | 0.71 | ALDH1A1 (0.34) | ALDH1A1KDM4ETDP1SMN1; SMN2NPBWR1 | |
| SCHEMBL8642476 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNASLC6A2SMN1; SMN2HTT | |
| SCHEMBL8148760 | 0.69 | LMNA (0.34) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL8146811 | 0.69 | TRPA1 (0.38) | ALDH1A1TRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL8731929 | 0.68 | LMNA (0.47) | ALDH1A1KDM4ETDP1TRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000013690-A1 | EXOCYCLIC-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |