Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | CCR1 | P32246 | 13/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962422 | 0.83 | OPRM1 (0.63) | OPRL1OPRM1OPRD1OPRK1CCR1 | |
| SCHEMBL3591425 | 0.74 | CCR3 (0.57) | OPRL1OPRM1OPRD1OPRK1CCR3 | |
| SCHEMBL7330890 | 0.71 | CYP2D6 (0.77) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7330874 | 0.71 | CYP2D6 (0.77) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL15543779 | 0.71 | MAPT (0.55) | OPRL1OPRM1OPRD1OPRK1CCR3 | |
| SCHEMBL5518359 | 0.71 | CCR3 (0.54) | OPRL1OPRM1OPRD1OPRK1CCR3 | |
| SCHEMBL29090112 | 0.71 | DRD2 (0.72) | OPRL1OPRM1OPRD1OPRK1CCR3 | |
| SCHEMBL3591423 | 0.71 | CCR3 (0.57) | OPRL1OPRM1OPRD1OPRK1CCR3 | |
| SCHEMBL11205205 | 0.71 | CCR3 (0.57) | OPRL1OPRM1OPRD1OPRK1CCR3 | |
| SCHEMBL21077853 | 0.71 | CCR3 (0.57) | OPRL1OPRM1OPRD1OPRK1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767131-A | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA, INHIBITION OF CHOLESTEROL SYNTHESIS, LOWERING OF INTRAOCULAR PRESSURE; ALPHA-ADRENERGIC RECEPTOR DISEASES | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |