Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27549736 | 0.90 | HCAR2 (0.80) | GAAHCAR2HDAC1KDM4ERAB9A | |
| SCHEMBL14340800 | 0.86 | HCAR2 (0.81) | GAAHCAR2KDM4E | |
| SCHEMBL8637193 | 0.85 | KMT2A (0.60) | GAAHCAR2HDAC1KDM4EMEN1 | |
| SCHEMBL13676190 | 0.82 | ALDH1A1 (0.58) | GAAHCAR2KDM4ERAB9AALDH1A1 | |
| SCHEMBL31239117 | 0.81 | RAB9A (0.80) | GAAHCAR2KDM4EMEN1PKM | |
| SCHEMBL8641094 | 0.81 | KMT2A (0.57) | GAAHCAR2KDM4EMEN1KMT2A | |
| SCHEMBL12725545 | 0.81 | MEN1 (0.60) | HCAR2HDAC1KDM4EMEN1PKM | |
| SCHEMBL14349717 | 0.79 | HCAR2 (1.00) | HCAR2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL8605379 | 0.79 | RAB9A (0.72) | GAAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL30522452 | 0.79 | KDM4E (0.74) | GAAHCAR2HDAC1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |