Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27300721 | 0.87 | HSD17B10 (0.48) | HSD17B10ALDH1A1 | |
| SCHEMBL7381785 | 0.87 | MME (0.48) | MMP8MMECASRGAAALDH1A1 | |
| SCHEMBL6276114 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8CASRSLC22A1GAA | |
| SCHEMBL3840238 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8CASRSLC22A1GAA | |
| SCHEMBL9773126 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8CASRSLC22A1GAA | |
| SCHEMBL9363838 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8CASRSLC22A1GAA | |
| SCHEMBL7257080 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2MMP8CASRSLC22A1GAA | |
| SCHEMBL27995630 | 0.79 | MMP8 (0.51) | SMN1; SMN2MMP8HSD17B10GAALMNA | |
| SCHEMBL10603601 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2MMP8CASRGAAALDH1A1 | |
| SCHEMBL20113912 | 0.77 | MMP8 (0.50) | SMN1; SMN2MMP8CASRGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |
| EP-0766694-A1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035307-A1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1995-12-28 | — | — | WO | disclosed |