Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773126 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8GAACASRCYP1A2 | |
| SCHEMBL9363838 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8GAACASRCYP1A2 | |
| SCHEMBL3840238 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8GAACASRCYP1A2 | |
| SCHEMBL9773175 | 0.86 | HSD17B10 (0.44) | SMN1; SMN2MMP8CASRCYP1A2CYP2D6 | |
| SCHEMBL10603601 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MMP8GAACASRTDP1 | |
| SCHEMBL9773237 | 0.86 | HSD17B10 (0.44) | SMN1; SMN2MMP8CASRCYP1A2CYP2D6 | |
| SCHEMBL8640339 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2MMP8GAACASRCYP1A2 | |
| SCHEMBL7257080 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2MMP8GAACASRCYP1A2 | |
| SCHEMBL20113912 | 0.81 | MMP8 (0.50) | SMN1; SMN2MMP8GAACASRTDP1 | |
| SCHEMBL9363415 | 0.81 | EPHX1 (0.49) | SMN1; SMN2CASRCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018156892-A1 | PEPTIDE INHIBITORS OF TRANSCRIPTION FACTOR AGGREGATION | ADRX, INC. (US) | 2018-08-30 | — | — | WO | disclosed |
| WO-2005121084-A1 | A METHOD OF PREPARATION OF RAMIPRIL | ZENTIVA, A. S. (CZ) | 2005-12-22 | — | — | WO | disclosed |
| US-20020087007-A1 | Process for preparing pharmacologically acceptable salt of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-amino acid | KANEKA CORPORATION (JP) | 2002-07-04 | — | — | US | disclosed |
| EP-0719280-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS HAVING ACE INHIBITORY ACTION AS WELL AS NOVEL COMPOUNDS USEFUL AS STARTING MATERIALS OR INTERMEDIATES IN SAID PROCESS | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. (SI) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002564-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS HAVING ACE INHIBITORY ACTION AS WELL AS NOVEL COMPOUNDS USEFUL AS STARTING MATERIALS OR INTERMEDIATES IN SAID PROCESS | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, D.D. (SI) | 1996-02-01 | — | — | WO | disclosed |
| EP-0434560-B1 | New derivatives of substituted aminoacids, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-01-26 | — | — | EP | disclosed |
| EP-0434560-A1 | New derivatives of substituted aminoacids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-06-26 | — | — | EP | disclosed |
| EP-0281393-A2 | Method for producing indan derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020087007-A1 | Process for preparing pharmacologically acceptable salt of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-amino acid | SLC7A1, ASS1, ALDH7A1 | SMN1; SMN2 496/4885MMP8 2984/4885GAA 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.