Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925320 | 0.80 | PTGS2 (0.47) | PTGS2PTGDR2 | |
| SCHEMBL6180483 | 0.79 | PTGS2 (0.53) | PTGS2SMN1; SMN2ALOX5ALDH1A1MAPK14 | |
| SCHEMBL5078441 | 0.79 | PTGS2 (0.53) | PTGS2SMN1; SMN2ALOX5ALDH1A1MAPK14 | |
| SCHEMBL8766048 | 0.79 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL4212020 | 0.78 | PTGS2 (0.52) | PTGS2SMN1; SMN2ALOX5ALDH1A1MAPK14 | |
| SCHEMBL8640384 | 0.78 | PTGS2 (0.45) | PTGS2PTGDR2 | |
| SCHEMBL18016057 | 0.77 | KMT2A (0.59) | PTGS2KMT2AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8925255 | 0.76 | PTGS2 (0.41) | PTGS2PTGDR2 | |
| SCHEMBL63779 | 0.76 | KMT2A (0.64) | KMT2AGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8926255 | 0.75 | PSD (0.47) | PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |