Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640336 | 0.83 | NISCH (0.33) | CCR2 | |
| SCHEMBL22475240 | 0.81 | CYP3A4 (0.36) | — | |
| SCHEMBL8641402 | 0.81 | HTR2C (0.34) | HRH3 | |
| SCHEMBL23280225 | 0.81 | NISCH (0.32) | CCR2 | |
| SCHEMBL8639828 | 0.81 | KIF11 (0.37) | PTGS1PTGS2 | |
| SCHEMBL8639213 | 0.81 | PTGS2 (0.35) | CCR2PTGS1PTGS2 | |
| SCHEMBL8640091 | 0.79 | CA12 (0.38) | PTGS1PTGS2HRH3 | |
| SCHEMBL23097130 | 0.79 | CA12 (0.38) | PTGS1PTGS2HRH3 | |
| SCHEMBL13211910 | 0.79 | PTGS2 (0.34) | PTGS1PTGS2 | |
| SCHEMBL23073355 | 0.78 | MAPK14 (0.49) | MAPK14GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |