Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936124 | 0.81 | ESR1 (0.47) | ESR1ESR2CNR2ALDH1A1PPARG | |
| SCHEMBL28238207 | 0.81 | ESR1 (0.47) | ESR1ESR2CNR2ALDH1A1PPARG | |
| SCHEMBL28222075 | 0.80 | ESR1 (0.46) | ESR1ESR2CNR2ALDH1A1NPY5R | |
| SCHEMBL1509141 | 0.80 | ESR1 (0.46) | ESR1ESR2CNR2ALDH1A1NPY5R | |
| SCHEMBL7633715 | 0.79 | PTGS2 (0.36) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19470216 | 0.78 | ACACB (0.49) | ESR1ESR2PPARGPPARA | |
| SCHEMBL13669682 | 0.77 | PTGS2 (0.47) | ESR1SLC6A4 | |
| SCHEMBL28344007 | 0.77 | ALDH1A1 (0.59) | ESR1ESR2CNR2ALDH1A1SLC6A4 | |
| SCHEMBL28344005 | 0.77 | ALDH1A1 (0.59) | ESR1ESR2CNR2ALDH1A1SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL5305768 | 0.76 | ALDH1A1 (0.58) | ESR1ESR2CNR2ALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730922-A | FLUOROCYCLOBUTANES | THE DOW CHEMICAL COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| US-5409777-A | Protective coatings | THE DOW CHEMICAL COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5246782-A | Electronic devices | THE DOW CHEMICAL COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0490335-A2 | Laminates of polymers having perfluorocyclobutane rings and polymers containing perfluorocyclobutane rings | THE DOW CHEMICAL COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |