SCHEMBL7633715

SCHEMBL7633715

FC(F)=C(F)Oc1ccc(CC(c2ccc(OC(F)=C(F)F)cc2)c2ccc(OC(F)=C(F)F)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.36
ESR1 P03372 3/20 0.36
ESR2 Q92731 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
LDHA P00338 1/20 0.36
PDE4A P27815 4/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
PTGS1 P23219 4/20 0.33
PTPN1 P18031 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
LMNA P02545 2/20 0.33
CYP2C9 P11712 2/20 0.33
AKR1C3 P42330 2/20 0.33
CXCR1 P25024 2/20 0.33
CXCR2 P25025 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13669682 0.80 PTGS2 (0.47) PTGS2ESR1SLC6A4PTGS1LMNA
SCHEMBL8640443 0.79 ESR1 (0.45) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL4530562 0.76 RAB9A (0.35) ESR1ESR2LMNA
SCHEMBL4711303 0.75 LTA4H (0.47) PPARGPPARATSHR
SCHEMBL13422210 0.74 LTA4H (0.52) CYP1A2CYP2D6CYP2C19PPARGPPARA
SCHEMBL12200929 0.73 SMN1; SMN2 (0.45) LMNA
SCHEMBL9006509 0.73 RAB9A (0.45) CYP2C19PPARGPPARALMNA
SCHEMBL8731268 0.73 TRPA1 (0.36) TSHR
SCHEMBL16713057 0.71 CYP1A2 (0.66) CYP1A2CYP2D6CYP2C19LDHAPDE4A
SCHEMBL4260460 0.70 THRB (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1267433-A2 Flow field structures for membrane electrode assemblies of fuel cells THE DOW CHEMICAL COMPANY (US) 2002-12-18 EP disclosed
EP-1267436-A2 Membrane electrode assemblies for fuel cells THE DOW CHEMICAL COMPANY (US) 2002-12-18 EP disclosed
US-5869416-A Electrode ink for membrane electrode assembly THE DOW CHEMICAL COMPANY (US) 1999-02-09 US disclosed
EP-0853824-A2 FLOW FIELD STRUCTURES FOR MEMBRANE ELECTRODE ASSEMBLIES OF FUEL CELLS THE DOW CHEMICAL COMPANY (US) 1998-07-22 EP disclosed
US-5702755-A Process for preparing a membrane/electrode assembly THE DOW CHEMICAL COMPANY (US) 1997-12-30 US disclosed
WO-1997013287-A9 FLOW FIELD STRUCTURES FOR MEMBRANE ELECTRODE ASSEMBLIES OF FUEL CELLS 1997-07-03 WO disclosed
US-5620807-A Flow field assembly for electrochemical fuel cells THE DOW CHEMICAL COMPANY (US) 1997-04-15 US disclosed
WO-1997013287-A2 FLOW FIELD STRUCTURES FOR MEMBRANE ELECTRODE ASSEMBLIES OF FUEL CELLS THE DOW CHEMICAL COMPANY (US) 1997-04-10 WO disclosed
US-5037917-A Polymerizing Monomers Containing At Least Two Perfluorovinyl Groups, Then Heating To Form Perfluorocyclobutane Rings THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed