SCHEMBL8640489

SCHEMBL8640489

C=CC(C(=O)O)c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ USP2 O75604 3/20 0.54
▸ POLB P06746 2/20 0.54
▸ ATM Q13315 1/20 0.54
▸ PLEC Q15149 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ CDC25A P30304 1/20 0.48
▸ CDC25B P30305 1/20 0.48
▸ CDC25C P30307 1/20 0.48
▸ ALPL P05186 1/20 0.48
▸ ALPI P09923 1/20 0.48
▸ ALPG P10696 1/20 0.48
▸ GNG2 P59768 1/20 0.46
▸ GNB1 P62873 1/20 0.46
▸ DNASE1L3 Q13609 1/20 0.43
▸ PRMT1 Q99873 1/20 0.43
▸ CA9 Q16790 5/20 0.42
▸ CA1 P00915 4/20 0.42
▸ CA2 P00918 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4435739 0.82 USP2 (0.57) MEN1KMT2AUSP2POLBATM
SCHEMBL12679617 0.79 KMT2A (0.59) MEN1KMT2AUSP2POLBATM
SCHEMBL8427558 0.75 USP2 (0.64) MEN1KMT2AUSP2POLBATM
SCHEMBL22043216 0.74 MEN1 (0.56) MEN1KMT2AUSP2POLBATM
SCHEMBL2792422 0.72 USP2 (0.57) MEN1KMT2AUSP2POLBATM
SCHEMBL2792418 0.72 USP2 (0.57) MEN1KMT2AUSP2POLBATM
SCHEMBL30887118 0.72 CA9 (0.66) MEN1KMT2AUSP2POLBATM
SCHEMBL2775968 0.72 USP2 (0.63) MEN1KMT2AUSP2POLBATM
SCHEMBL20254033 0.71 USP2 (0.77) MEN1KMT2AUSP2POLBATM
SCHEMBL24454976 0.71 DNASE1L3 (0.65) MEN1KMT2AUSP2POLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252683-B1 Process and reagents for DNA sequence analysis DU PONT (US) 1995-01-18 — — EP claimed
EP-0252683-A2 Process and reagents for DNA sequence analysis E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-13 — — EP claimed
JP-10158530-A — — None — — JP disclosed
JP-9124636-A — — None — — JP disclosed
JP-H10158530-A FLUORESCENT DYE AND ITS PRODUCTION E I DU PONT DE NEMOURS & CO 1998-06-16 — — JP disclosed
JP-H09124636-A FLUORESCENT DYE E I DU PONT DE NEMOURS & CO 1997-05-13 — — JP disclosed
EP-0252683-B1 Process and reagents for DNA sequence analysis DU PONT (US) 1995-01-18 — — EP disclosed
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