SCHEMBL4435739

SCHEMBL4435739

CC(C(=O)O)c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ POLB P06746 2/20 0.57
▸ ATM Q13315 1/20 0.57
▸ PLEC Q15149 1/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ CDC25A P30304 1/20 0.51
▸ CDC25B P30305 1/20 0.51
▸ CDC25C P30307 1/20 0.51
▸ ALPL P05186 1/20 0.51
▸ ALPI P09923 1/20 0.51
▸ ALPG P10696 1/20 0.51
▸ GNG2 P59768 1/20 0.51
▸ GNB1 P62873 1/20 0.51
▸ AKR1B1 P15121 3/20 0.44
▸ DNASE1L3 Q13609 1/20 0.43
▸ PRMT1 Q99873 1/20 0.43
▸ HPGD P15428 3/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12679617 0.87 KMT2A (0.59) USP2MEN1KMT2APOLBATM
SCHEMBL8640489 0.82 MEN1 (0.54) USP2MEN1KMT2APOLBATM
SCHEMBL8427558 0.78 USP2 (0.64) USP2MEN1KMT2APOLBATM
SCHEMBL2775968 0.77 USP2 (0.63) USP2MEN1KMT2APOLBATM
SCHEMBL21151072 0.75 KMT2A (0.60) USP2MEN1KMT2APOLBATM
SCHEMBL16231514 0.75 USP2 (0.61) USP2MEN1KMT2APOLBATM
SCHEMBL12637647 0.74 USP2 (0.72) USP2MEN1KMT2APOLBATM
SCHEMBL16231515 0.74 USP2 (0.60) USP2MEN1KMT2APOLBATM
SCHEMBL13320808 0.74 KMT2A (0.59) USP2MEN1KMT2APOLBATM
SCHEMBL16019277 0.74 USP2 (0.59) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180172712-A1 METHODS AND MATERIALS FOR ASSESSING HYDROGEN PEROXIDE ACCUMULATION IN CELLS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2018-06-21 — — US disclosed
WO-2016205538-A1 METHODS AND MATERIALS FOR ASSESSING HYDROGEN PEROXIDE ACCUMULATION IN CELLS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2016-12-22 — — WO disclosed
US-9430610-B2 Re-sequencing pathogen microarray THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-08-30 — — US disclosed
US-20090170717-A1 RE-SEQUENCING PATHOGEN MICROARRAY THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-07-02 — — US disclosed
EP-1778881-A4 RESEQUENCING PATHOGEN MICROARRAY US GOV SEC NAVY (US) 2008-12-10 — — EP disclosed
EP-1185699-B1 MICROARRAY-BASED SUBTRACTIVE HYBRIDIZATION AVENTIS PHARMA INC (US) 2007-12-26 — — EP disclosed
EP-1778881-A2 RESEQUENCING PATHOGEN MICROARRAY The Government of the United States of America as represented by The Secretary of the Navy (US) 2007-05-02 — — EP disclosed
US-7157230-B2 Electron induced fluorescent method for nucleic acid sequencing INTEL CORPORATION (US) 2007-01-02 — — US disclosed
US-20060228717-A1 Microfluidic system and method of utilization AGILENT TECHNOLOGIES, INC. 2006-10-12 — — US disclosed
EP-1710562-A2 Microfluidic system and method of utilization Agilent Technologies, Inc. (US) 2006-10-11 — — EP disclosed
US-5102785-A Cleaving to produce DNA fragment which are then end labeled with reporter, again cleaved to produce short fragment, separatiion; analysis E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-07 — — US disclosed
US-5047519-A Alkynylamino-nucleotides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-09-10 — — US disclosed
WO-1991005605-A1 CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-05-02 — — WO disclosed
WO-1991002040-A1 CYCLODEXTRIN LABELS FOR NUCLEIC ACID AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-02-21 — — WO disclosed
US-4833332-A Scanning fluorescent detection system E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-23 — — US disclosed
EP-0309969-A2 Method of gene mapping E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-05 — — EP disclosed
EP-0294996-A2 Scanning fluorescent detection system E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-12-14 — — EP disclosed
EP-0252683-A2 Process and reagents for DNA sequence analysis E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-13 — — EP disclosed
EP-0252683-A2 Process and reagents for DNA sequence analysis E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-13 — — EP disclosed
EP-0251786-A2 Alkynylamino-nucleotides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-07 — — EP disclosed
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