Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 19/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 19/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 18/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245660 | 0.83 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BHRH1 | |
| SCHEMBL6782951 | 0.80 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BHRH1 | |
| SCHEMBL6245662 | 0.77 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BHRH1 | |
| SCHEMBL6201664 | 0.74 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BHRH1 | |
| SCHEMBL6782946 | 0.74 | ADRA1D (0.63) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6785271 | 0.73 | ADRA1A (0.50) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6201662 | 0.69 | ADRA1D (0.61) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9053325 | 0.68 | DRD2 (0.72) | ADRA1AHRH1 | |
| SCHEMBL6785268 | 0.67 | ADRA1D (0.60) | ADRA1DADRA1AADRA1B | |
| SCHEMBL1594237 | 0.66 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998051311-A2 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-11-19 | — | — | WO | disclosed |