Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331308 | 0.85 | CMA1 (0.33) | RECQLSMN1; SMN2RAB9APKMCMA1 | |
| SCHEMBL7905018 | 0.84 | GSK3A (0.36) | — | |
| SCHEMBL11615801 | 0.79 | RELA (0.39) | TRPA1MAOBNFE2L2CYP19A1MAOA | |
| SCHEMBL4596796 | 0.72 | HCAR2 (0.36) | PKMLMNAALDH1A1ALOX5MAPK1 | |
| SCHEMBL25057557 | 0.69 | MAOB (0.39) | TRPA1MAOBLMNAALDH1A1NFE2L2 | |
| SCHEMBL2030189 | 0.69 | — | — | |
| SCHEMBL4438933 | 0.69 | MAOB (0.39) | CMA1TRPA1MAOBNFE2L2CYP19A1 | |
| SCHEMBL4065553 | 0.68 | CFTR (0.37) | SMN1; SMN2RAB9AMAOBLMNAALDH1A1 | |
| (Z)-1,2-Diphenylethene SCHEMBL272984 | 0.68 | MAOB (0.52) | RECQLSMN1; SMN2CMA1TRPA1MAOB | |
| Hydrochloric Acid SCHEMBL12003783 | 0.68 | MAOB (0.38) | CMA1TRPA1MAOBNFE2L2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365696-A | Compounds and compositions as modulators of steroid hormone nuclear receptors | IRM LLC (BM) | 2009-02-11 | — | — | CN | disclosed |
| EP-0664014-B1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL NV (NL) | 1998-08-19 | — | — | EP | disclosed |
| EP-0664014-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | Akzo Nobel N.V. (NL) | 1995-07-26 | — | — | EP | disclosed |
| EP-0445864-B1 | Thermally curable NLO system and integrated optical components prepared therefrom | AKZO NOBEL NV (NL) | 1994-08-24 | — | — | EP | disclosed |
| WO-1994008269-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL N.V. (NL) | 1994-04-14 | — | — | WO | disclosed |
| EP-0445864-A1 | Thermally curable NLO system and integrated optical components prepared therefrom | Akzo Nobel N.V. (NL) | 1991-09-11 | — | — | EP | disclosed |