Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348362 | 0.91 | ALDH1A1 (0.42) | HRH1ALDH1A1LMNATSHRUSP2 | |
| SCHEMBL8636037 | 0.90 | PKM (0.51) | ALDH1A1PKMCYP1A2L3MBTL1 | |
| SCHEMBL8641320 | 0.89 | ALDH1A1 (0.52) | HRH1ALDH1A1PKMCYP1A2L3MBTL1 | |
| SCHEMBL8639995 | 0.89 | CYP3A4 (0.47) | HRH1ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL8355592 | 0.88 | ALDH1A1 (0.51) | HRH1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8353688 | 0.88 | KDM4E (0.46) | HRH1ALDH1A1CYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL8636055 | 0.87 | PKM (0.43) | HRH1ALDH1A1PKMCYP1A2CYP3A4 | |
| SCHEMBL8640612 | 0.86 | ALDH1A1 (0.41) | HRH1ALDH1A1LMNAPKMSMN1; SMN2 | |
| SCHEMBL8636579 | 0.85 | TACR2 (0.46) | HRH1CYP3A4 | |
| SCHEMBL8347206 | 0.85 | TACR2 (0.51) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |