SCHEMBL8640837

SCHEMBL8640837

CCN(CC)CCCNC(=O)c1ccccc1O

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.67
APP P05067 7/20 0.64
ALDH1A1 P00352 2/20 0.59
HPGD P15428 2/20 0.59
KDM4E B2RXH2 1/20 0.59
TSHR P16473 2/20 0.58
HTT P42858 2/20 0.58
NPC1 O15118 1/20 0.58
MAPT P10636 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HSD17B10 Q99714 1/20 0.58
NLRP1 Q9C000 1/20 0.58
GAA P10253 1/20 0.53
ALOX5 P09917 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salethamide SCHEMBL588724 0.91 ALDH1A1 (0.71) NAAAAPPALDH1A1HPGDKDM4E
SCHEMBL12704467 0.90 NAAA (0.74) NAAAAPPALDH1A1HPGDTSHR
Salethamide SCHEMBL11573255 0.90 ALDH1A1 (0.69) NAAAAPPALDH1A1HPGDKDM4E
SCHEMBL9680149 0.85 APP (0.61) APPALDH1A1HPGDKDM4ETSHR
SCHEMBL13162944 0.85 HPGD (0.61) APPALDH1A1HPGDKDM4ETSHR
SCHEMBL8639193 0.85 ALDH1A1 (0.66) NAAAAPPALDH1A1HPGDKDM4E
SCHEMBL13317641 0.85 NAAA (0.58) NAAAAPPALDH1A1HPGDKDM4E
Hydrochloric Acid SCHEMBL11319796 0.84 ALDH1A1 (0.64) NAAAAPPALDH1A1HPGDKDM4E
Salethamide SCHEMBL126228 0.83 ALDH1A1 (0.61) NAAAAPPALDH1A1HPGDKDM4E
SCHEMBL11331280 0.83 APP (0.70) APPALDH1A1HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753407-A Polyamic acid composition KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-19 US disclosed
US-5585217-A Polyamic acid composition KABUSHIKI KAISHA TOSHIBA (JP) 1996-12-17 US disclosed