SCHEMBL8640947

SCHEMBL8640947

C=C(CC(=O)O)C(=O)OC(C)(C)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
THRB P10828 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639457 0.89 ALOX15 (0.34) ALOX15HSD17B10TET2
SCHEMBL8640945 0.86
SCHEMBL4925405 0.82 ALOX15 (0.36) ALOX15HSD17B10TET2
SCHEMBL5704646 0.79 THRB (0.39) ALOX15HSD17B10THRBTET2
SCHEMBL15153790 0.79 THRB (0.39) ALOX15HSD17B10THRBTET2
SCHEMBL8640179 0.78 THRB (0.31) THRB
SCHEMBL2367894 0.78 ALOX15 (0.36) ALOX15HSD17B10TET2
SCHEMBL7085941 0.77 ALOX15 (0.39) ALOX15HSD17B10TET2
SCHEMBL5889823 0.77
SCHEMBL8640185 0.77 THRB (0.37) ALOX15HSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5851422-A Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1998-12-22 US disclosed
EP-0790289-A1 Polymeric material for liquid crystal/polymer composite film, liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1997-08-20 EP disclosed