Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537675 | 0.86 | ALDH1A1 (0.35) | KMT2ANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8652790 | 0.81 | KDM4E (0.33) | KDM4E | |
| SCHEMBL8623813 | 0.80 | GRM5 (0.31) | — | |
| SCHEMBL1412582 | 0.79 | TP53 (0.42) | KMT2ARAB9AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL22900489 | 0.76 | KMT2A (0.46) | KMT2AUSP2NPC1RAB9AALDH1A1 | |
| SCHEMBL12682954 | 0.75 | ADORA1 (0.42) | KMT2AUSP2NPC1RAB9AALDH1A1 | |
| SCHEMBL1412587 | 0.75 | ELANE (0.39) | KMT2ANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL3797706 | 0.74 | ADORA3 (0.41) | KMT2AUSP2NPC1RAB9AALDH1A1 | |
| SCHEMBL12683029 | 0.74 | CYP1A2 (0.46) | KMT2AUSP2NPC1RAB9AALDH1A1 | |
| SCHEMBL4700865 | 0.73 | ADORA3 (0.47) | KMT2ANPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923558-A1 | SUBSTITUTED 1-(3-PYRAZOLYL)-PYRAZOLES | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006702-A1 | SUBSTITUTED 1-(3-PYRAZOLYL)-PYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |