SCHEMBL86420

SCHEMBL86420

O=C1COc2cc3c(cc21)OCO3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
PKM P14618 2/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2D6 P10635 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
MAPT P10636 1/20 0.37
PAX8 Q06710 1/20 0.37
CMA1 P23946 1/20 0.37
NPC1 O15118 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86325 0.79 MAOB (0.53) ACHEKDM4EALDH1A1MAOAMAOB
SCHEMBL12341987 0.75 KDM4E (0.50) ACHEKDM4EALDH1A1MAPK1MAOA
SCHEMBL20963316 0.75 CYP2D6 (0.47) ACHEKDM4EALDH1A1MAPK1PKM
SCHEMBL16357239 0.74 MAPT (0.42) KDM4EALDH1A1MAPK1MAOAMAOB
SCHEMBL19627183 0.74 IMPDH2 (0.47) KDM4EALDH1A1MAOAMAOBPKM
SCHEMBL1134704 0.72 CYP3A4 (0.48) ACHEKDM4EALDH1A1MAPK1PKM
SCHEMBL10922851 0.72 MAPT (0.60) KDM4EALDH1A1MAOAMAOBPKM
SCHEMBL3904370 0.72 PKM (0.54) ACHEKDM4EALDH1A1MAPK1PKM
SCHEMBL25209908 0.71 CDC25B (0.42) ACHEKDM4EALDH1A1MAPK1MAOA
SCHEMBL86315 0.71 MAOA (0.50) KDM4EALDH1A1MAOAMAOBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319330-B2 Tricyclic furan-substituted piperidinedione compound MEDSHINE DISCOVERY INC. (CN) 2022-05-03 US disclosed
US-20210317138-A1 TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND MEDSHINE DISCOVERY INC. (CN) 2021-10-14 US disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
EP-2682272-B1 INK JET RECORDING METHOD AND PRINTED MATERIAL FUJIFILM CORP (JP) 2015-08-26 EP disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8168263-B2 Photo-curable composition, ink composition, and inkjet recording method using the ink composition FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168263-B2 Photo-curable composition, ink composition, and inkjet recording method using the ink composition FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20090087576-A1 INK COMPOSITION FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087576-A1 INK COMPOSITION FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042563-A1 Photocurable coating composition, and overprint and process for producing same FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
EP-2042573-A1 Ink composition FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319330-B2 Tricyclic furan-substituted piperidinedione compound CRBN, PFDN1, CLNS1A ACHE 2659/4885KDM4E 2404/4885ALDH1A1 2383/4885
US-20210317138-A1 TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND CRBN, PFDN1, CLNS1A ACHE 2659/4885KDM4E 2404/4885ALDH1A1 2383/4885
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 ACHE 911/4885KDM4E 679/4885ALDH1A1 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.