Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.40 |
| ▸ | RARB | P10826 | 7/20 | 0.40 |
| ▸ | RARG | P13631 | 6/20 | 0.40 |
| ▸ | RXRB | P28702 | 7/20 | 0.39 |
| ▸ | RXRG | P48443 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641120 | 0.92 | LMNA (0.44) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8560364 | 0.83 | CYP3A4 (0.38) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8559347 | 0.81 | KDM4E (0.43) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6292641 | 0.80 | RXRA (0.52) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8558259 | 0.76 | F2 (0.38) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6292635 | 0.76 | RARA (0.62) | RARBRARGRARAKMT2ATDP1 | |
| SCHEMBL7162481 | 0.74 | RXRA (0.43) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6292634 | 0.73 | RXRA (0.45) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6294342 | 0.72 | RARA (0.69) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6297133 | 0.72 | RARA (0.48) | RXRARARBRARGRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723666-A | USEFUL AS REGULATORS OF CELL PROLIFERATION AND DIFFERENTIATION | ALLERGAN (US) | 1998-03-03 | — | — | US | disclosed |