SCHEMBL8642196

SCHEMBL8642196

NCCCCCC(N)C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.47
EPHX1 P07099 1/20 0.41
DPP4 P27487 5/20 0.40
TP53 P04637 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CPB2 Q96IY4 2/20 0.35
DPP7 Q9UHL4 3/20 0.35
DPP8 Q6V1X1 2/20 0.35
FAP Q12884 1/20 0.33
DPP9 Q86TI2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4785319 0.98 SIGMAR1 (0.43) SIGMAR1EPHX1DPP4TP53LMNA
SCHEMBL4243546 0.91 EPHX1 (0.44) SIGMAR1EPHX1DPP4TP53KDM4E
SCHEMBL10866419 0.91 EPHX1 (0.42) SIGMAR1EPHX1DPP4TP53KDM4E
SCHEMBL11434637 0.91 EPHX1 (0.42) SIGMAR1EPHX1DPP4TP53KDM4E
SCHEMBL11301452 0.91 EPHX1 (0.42) SIGMAR1EPHX1DPP4TP53KDM4E
SCHEMBL8966754 0.89 EPHX1 (0.41) SIGMAR1EPHX1DPP4TP53KDM4E
SCHEMBL11132748 0.89 SIGMAR1 (0.39) SIGMAR1EPHX1DPP4TP53KDM4E
SCHEMBL3834490 0.89 EPHX1 (0.44) SIGMAR1EPHX1DPP4TP53KDM4E
SCHEMBL25562386 0.87 GSR (0.38) SIGMAR1DPP4LMNABLMDPP7
SCHEMBL28341935 0.85 EPHX1 (0.43) SIGMAR1EPHX1DPP4TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190023613-A1 Reaction Resin Composition, Multi-Component System and Use Thereof HILTI AKTIENGESELLSCHAFT (LI) 2019-01-24 US disclosed
EP-0845058-A1 FIBROUS WEBS HAVING ENHANCED ELECTRET PROPERTIES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-06-03 EP disclosed