Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243546 | 0.98 | EPHX1 (0.44) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL19988099 | 0.95 | EPHX1 (0.36) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL4785319 | 0.91 | SIGMAR1 (0.43) | EPHX1DPP4TP53SIGMAR1LMNA | |
| SCHEMBL8642196 | 0.89 | SIGMAR1 (0.47) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL28430462 | 0.85 | EPHX1 (0.44) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL11132748 | 0.85 | SIGMAR1 (0.39) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL3834490 | 0.85 | EPHX1 (0.44) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL1397325 | 0.83 | EPHX1 (0.48) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL11301452 | 0.83 | EPHX1 (0.42) | EPHX1DPP4TP53SIGMAR1KDM4E | |
| SCHEMBL11434637 | 0.83 | EPHX1 (0.42) | EPHX1DPP4TP53SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554787-A | CHEMICAL INTERMEDIATES FOR POLYURETHANES | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| EP-0449110-B1 | 2,2-Dialkylpentane-1,5-diisocyanates, -diurethanes, and -dicarbamic acid chlorides, process for their preparation and their use | BASF AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0452693-B1 | Method of preparing 2,2-disubstituted pentane 1,5-diamines | BASF AG (DE) | 1995-10-04 | — | — | EP | disclosed |
| US-5166443-A | PREPARATION OF 2,2-DISUBSTITUTED PENTANE-1,5-DIAMINES | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0452693-A1 | Method of preparing 2,2-disubstituted pentane 1,5-diamines | BASF Aktiengesellschaft (DE) | 1991-10-23 | — | — | EP | disclosed |
| EP-0449110-A2 | 2,2-Dialkylpentane-1,5-diisocyanates, -diurethanes, and -dicarbamic acid chlorides, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1991-10-02 | — | — | EP | disclosed |