Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642196 | 0.98 | SIGMAR1 (0.47) | SIGMAR1EPHX1DPP4DPP7DPP8 | |
| SCHEMBL8966754 | 0.91 | EPHX1 (0.41) | SIGMAR1EPHX1DPP4DPP7DPP8 | |
| SCHEMBL11132748 | 0.91 | SIGMAR1 (0.39) | SIGMAR1EPHX1DPP4TP53LMNA | |
| SCHEMBL4243546 | 0.89 | EPHX1 (0.44) | SIGMAR1EPHX1DPP4TP53LMNA | |
| SCHEMBL11301452 | 0.89 | EPHX1 (0.42) | SIGMAR1EPHX1DPP4TP53LMNA | |
| SCHEMBL11434637 | 0.89 | EPHX1 (0.42) | SIGMAR1EPHX1DPP4TP53LMNA | |
| SCHEMBL10866419 | 0.89 | EPHX1 (0.42) | SIGMAR1EPHX1DPP4TP53LMNA | |
| SCHEMBL25562386 | 0.89 | GSR (0.38) | SIGMAR1DPP4DPP7DPP8CA12 | |
| SCHEMBL19988099 | 0.86 | EPHX1 (0.36) | SIGMAR1EPHX1DPP4TP53LMNA | |
| SCHEMBL3834490 | 0.86 | EPHX1 (0.44) | SIGMAR1EPHX1DPP4TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089010-A1 | PREPARATION OF SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |