Goserelin

Goserelin

SCHEMBL8643

CC(C)C[C@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NNC(N)=O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GNRHR

The experimentally established mechanism targets of Goserelin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GNRHR known ✓ P30968 2/20 0.63
ABCC2 Q92887 1/20 0.63
PTGS1 P23219 1/20 0.62
C5AR1 P21730 2/20 0.55
APLNR P35414 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Goserelin SCHEMBL7544569 1.00 GNRHR (0.63) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL25243029 1.00 GNRHR (0.63) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL14193129 1.00 GNRHR (0.63) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL29833872 1.00 GNRHR (0.63) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL13660188 1.00 GNRHR (0.63) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL4080889 1.00 GNRHR (0.62) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL6094 0.99 ABCC2 (0.64) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL14485644 0.99 ABCC2 (0.64) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL22367929 0.99 ABCC2 (0.64) GNRHRABCC2PTGS1C5AR1APLNR
Goserelin SCHEMBL6866961 0.99 GNRHR (0.63) GNRHRABCC2PTGS1C5AR1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 85465 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
CN-116209439-B Cereblon protein modulators Saint Jude Children's Research Hospital Ltd. (US) 2026-05-26 CN claimed
WO-2026105121-A1 ANTICANCER FORMULATIONS AND USES THEREOF INTRAGEL THERAPEUTICS LTD. (IL) 2026-05-21 WO claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
WO-2026098706-A1 USE IN TREATING BREAST CANCER AFTER TREATMENT WITH CDK4/6 INHIBITOR 正大天晴药业集团股份有限公司 2026-05-15 WO claimed
CN-122055165-A Combination treatment of prostate cancer with two bispecific antibodies 詹森生物科技公司 2026-05-15 CN claimed
WO-2026102332-A1 NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF Blaze Bioscience, Inc. (US) 2026-05-15 WO claimed
US-12624049-B2 Salt and crystal forms of 4-amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-z-yl)thieno[2.3-b]pyridin-6(7H)-one UNIVERSITY HEALTH NETWORK (CA) 2026-05-12 US claimed
US-12622976-B2 Targeting CLPTM1L for treatment and prevention of cancer THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) 2026-05-12 US claimed
CN-122029214-A Phospholipid drug conjugate and preparation method and application thereof 上海弼领生物技术有限公司 2026-05-12 CN claimed
EP-0538443-A4 METHODS AND FORMULATIONS FOR USE IN INHIBITING CONCEPTION AND IN TREATING BENIGN GYNECOLOGICAL DISORDERS 1993-12-08 EP claimed
WO-1993015722-A1 CONTROLLED DELIVERY OF PHARMACEUTICALS FROM PREFORMED POROUS MICROPARTICLES SYNTEX (USA) INC. (US) 1993-08-19 WO claimed
US-5211952-A Drug delivery of gonadotropin hormone releasing hormones for time release UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-05-18 US claimed
EP-0538443-A1 METHODS AND FORMULATIONS FOR USE IN INHIBITING CONCEPTION AND IN TREATING BENIGN GYNECOLOGICAL DISORDERS. UNIV SOUTHERN CALIFORNIA (US) 1993-04-28 EP claimed
EP-0518655-A2 Solid phase peptide synthesis ZENECA LIMITED (GB) 1992-12-16 EP claimed
EP-0518656-A2 Solid phase peptide synthesis ZENECA LIMITED (GB) 1992-12-16 EP claimed
WO-1992018107-A1 METHODS AND FORMULATIONS FOR USE IN INHIBITING CONCEPTION AND IN TREATING BENIGN GYNECOLOGICAL DISORDERS THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-10-29 WO claimed
US-5143661-A Silicone-hardened pharmaceutical microcapsules AMERICAN CYANAMID COMPANY (US) 1992-09-01 US claimed
EP-0312052-A1 Intranasal administration of polypeptides in powdered form SYNTEX (U.S.A.) INC. (US) 1989-04-19 EP claimed
EP-0058481-B1 CONTINUOUS RELEASE PHARMACEUTICAL COMPOSITIONS ZENECA LIMITED (GB) 1986-10-01 EP claimed