Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23370065 | 0.84 | AOC2 (0.55) | AOC2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL30361453 | 0.84 | AOC2 (0.55) | AOC2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5140258 | 0.84 | AOC2 (0.55) | AOC2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL28170343 | 0.84 | AOC2 (0.51) | AOC2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL4961361 | 0.80 | AOC2 (0.51) | AOC2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL1938543 | 0.80 | AOC2 (0.51) | AOC2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL21820745 | 0.76 | CRBN (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4595077 | 0.76 | CRBN (0.55) | AOC2MEN1KMT2AALDH1A1CRBN | |
| SCHEMBL28956797 | 0.76 | SLC12A2 (0.49) | AOC2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23732536 | 0.76 | MMP2 (0.48) | AOC2SMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744465-A | Method of inhibiting a β-lactamase enzyme by administering novel 2-thiosubstituted carbapenems | AMERICAN CYANAMID COMPANY (US) | 1998-04-28 | — | — | US | disclosed |