Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350848 | 0.82 | PYCR1 (0.46) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL3299248 | 0.79 | PYCR1 (0.47) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL6547406 | 0.79 | TAAR1 (0.48) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL168406 | 0.77 | PYCR1 (0.46) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL10753414 | 0.76 | TAAR1 (0.42) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL1610769 | 0.75 | PYCR1 (0.44) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL16918930 | 0.75 | PYCR1 (0.44) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL608419 | 0.75 | PYCR1 (0.44) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL96044 | 0.75 | TAAR1 (0.50) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL1145816 | 0.75 | PYCR1 (0.44) | PYCR1TDP1TP53ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750556-A | REDUCING DOPAMINE SYNTHESIS AND RELEASE, SCHIZOPHRENIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |