Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644173 | 1.00 | KMT2A (0.43) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL8650900 | 0.81 | KMT2A (0.39) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL8648112 | 0.81 | ALDH1A1 (0.60) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL8648115 | 0.81 | ALDH1A1 (0.60) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL7666255 | 0.79 | AKR1C1 (0.58) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL7218667 | 0.79 | AKR1C1 (0.58) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL27561721 | 0.78 | KMT2A (0.40) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL8643112 | 0.78 | KMT2A (0.37) | KMT2AALDH1A1LMNANPSR1HPGD | |
| SCHEMBL8643116 | 0.74 | KMT2A (0.37) | KMT2AALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL9239140 | 0.72 | ALDH1A1 (0.51) | KMT2AALDH1A1LMNANPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861831-A1 | HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |