Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666908 | 0.96 | LMNA (0.54) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL7666912 | 0.96 | LMNA (0.54) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL7666255 | 0.88 | AKR1C1 (0.58) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL7218667 | 0.88 | AKR1C1 (0.58) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL28512248 | 0.84 | MAPT (0.52) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL9226532 | 0.82 | LMNA (0.51) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL28771675 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL8805362 | 0.79 | KMT2A (0.58) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL8805358 | 0.79 | KMT2A (0.58) | ALDH1A1KMT2ALMNANPSR1MEN1 | |
| SCHEMBL4006382 | 0.78 | KMT2A (0.69) | ALDH1A1KMT2ALMNANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617621-A4 | CENTRAL CHOLECYSTOKININ ANTAGONISTS HAVING PHARMACEUTICAL ACTIVITY. | MERCK SHARP & DOHME (GB) | 1995-04-05 | — | — | EP | disclosed |
| EP-0617621-A1 | CENTRAL CHOLECYSTOKININ ANTAGONISTS HAVING PHARMACEUTICAL ACTIVITY | MERCK SHARP & DOHME LTD. (GB) | 1994-10-05 | — | — | EP | disclosed |