SCHEMBL864418

SCHEMBL864418

Nc1ncnc2c1ncn2C1C=C(CF)C(O)C1O

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHCY P23526 12/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12280561 1.00 AHCY (0.81) AHCY
Hydrochloric Acid SCHEMBL2484066 0.99 AHCY (0.80) AHCY
Hydrochloric Acid SCHEMBL2412144 0.99 AHCY (0.80) AHCY
SCHEMBL13825262 0.91 AHCY (0.80) AHCY
Neoplanocin A SCHEMBL863873 0.90 AHCY (1.00) AHCY
Neoplanocin A SCHEMBL12157269 0.90 AHCY (1.00) AHCY
Neoplanocin A SCHEMBL17117192 0.90 AHCY (1.00) AHCY
Neoplanocin A SCHEMBL10576831 0.90 AHCY (1.00) AHCY
Neoplanocin A SCHEMBL10469277 0.90 AHCY (1.00) AHCY
Neoplanocin A SCHEMBL30001474 0.90 AHCY (1.00) AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2522352-B1 Methods for stem cells modulation AGENCY SCIENCE TECH & RES (SG) 2017-01-11 EP disclosed
US-20160015693-A1 METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR AGENCY SCIENCE TECH & RES (SG) 2016-01-21 US disclosed
US-8969313-B2 Methods and compounds for preventing and treating a tumour AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-03-03 US disclosed
EP-1993553-B1 METHODS FOR CANCER THERAPY AND STEM CELL MODULATION AGENCY SCIENCE TECH & RES (SG) 2013-05-08 EP disclosed
EP-2522352-A1 Methods for cancer therapy and stem cell modulation Agency for Science, Technology and Research (SG) 2012-11-14 EP disclosed
US-8211869-B2 Methods for cancer therapy and stem cell modulation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-07-03 US disclosed
US-20120077841-A1 METHODS FOR CANCER THERAPY AND STEM CELL MODULATION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-29 US disclosed
US-8058258-B2 Methods for cancer therapy and stem cell modulation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-11-15 US disclosed
US-20110053882-A1 METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-03-03 US disclosed
EP-2217240-A1 METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR Agency for Science, Technology And Research (SG) 2010-08-18 EP disclosed
US-20100075915-A1 METHODS FOR CANCER THERAPY AND STEM CELL MODULATION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-03-25 US disclosed
WO-2009058102-A1 METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-05-07 WO disclosed
EP-1993553-A1 METHODS FOR CANCER THERAPY AND STEM CELL MODULATION Agency for Science, Technology and Research (SG) 2008-11-26 EP disclosed
WO-2007100304-A1 METHODS FOR CANCER THERAPY AND STEM CELL MODULATION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2007-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053882-A1 METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR HDAC1, CCAR2, HDAC11 AHCY 340/4885
US-20100075915-A1 METHODS FOR CANCER THERAPY AND STEM CELL MODULATION MCL1, BCOR, BCL2 AHCY 2998/4885
US-20160015693-A1 METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR HDAC1, HDAC11, CCAR2 AHCY 329/4885
US-20120077841-A1 METHODS FOR CANCER THERAPY AND STEM CELL MODULATION HCCS, MCL1, AHR AHCY 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.