Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | TLR4 | O00206 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307760 | 1.00 | RAB9A (1.00) | RAB9AALOX5ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9265860 | 0.90 | RAB9A (0.82) | RAB9AALOX5ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10400372 | 0.86 | RAB9A (0.74) | RAB9AALOX5MAOBMAOANPC1 | |
| SCHEMBL9311302 | 0.84 | RAB9A (0.73) | RAB9AALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL6965889 | 0.84 | RAB9A (0.73) | RAB9AALOX5ALDH1A1KDM4ETLR4 | |
| SCHEMBL22894438 | 0.84 | RAB9A (0.72) | RAB9AALOX5SPHK2SPHK1TLR4 | |
| SCHEMBL8545870 | 0.83 | RAB9A (0.71) | RAB9AALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL865349 | 0.83 | RAB9A (0.71) | RAB9AALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL23223734 | 0.82 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL11614936 | 0.82 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |
| US-9150678-B2 | Photoreactive polymer and alignment layer comprising the same | LG CHEM, LTD. (KR) | 2015-10-06 | — | — | US | disclosed |
| US-9151988-B2 | Cyclic olefin compound, photoreactive polymer, and alignment layer comprising the same | LG CHEM, LTD. (KR) | 2015-10-06 | — | — | US | disclosed |
| US-20150210792-A1 | PHOTO-ALIGNMENT POLYMER, ALIGNMENT LAYER AND LIQUID CRYSTAL RETARDATION FILM COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2015-07-30 | — | — | US | disclosed |
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-09 | — | — | US | disclosed |
| US-20150093520-A1 | CYCLIC OLEFIN COMPOUND, PHOTOREACTIVE POLYMER, AND ALIGNMENT LAYER COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2015-04-02 | — | — | US | disclosed |
| US-8946366-B2 | Cyclic olefin compound, photoreactive polymer, and alignment layer comprising the same | LG CHEM, LTD. (KR) | 2015-02-03 | — | — | US | disclosed |
| EP-2623527-A2 | LIGHT-SENSITIVE POLYMER AND ALIGNMENT LAYER INCLUDING SAME | LG Chem, Ltd. (KR) | 2013-08-07 | — | — | EP | disclosed |
| WO-2013086131-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-13 | — | — | WO | disclosed |
| EP-2547641-A2 | CYCLIC OLEFIN COMPOUND, PHOTOREACTIVE POLYMER AND ALIGNMENT LAYER COMPRISING THE SAME | LG Chem, Ltd. (KR) | 2013-01-23 | — | — | EP | disclosed |
| WO-2012044020-A2 | CYCLIC OLEFIN COMPOUND, PHOTOREACTIVE POLYMER AND ALIGNMENT LAYER COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2012-04-05 | — | — | WO | disclosed |
| US-20120075560-A1 | PHOTOREACTIVE POLYMER AND ALIGNMENT LAYER COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2012-03-29 | — | — | US | disclosed |
| US-20120076954-A1 | CYCLIC OLEFIN COMPOUND, PHOTOREACTIVE POLYMER, AND ALIGNMENT LAYER COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2012-03-29 | — | — | US | disclosed |
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-6251928-B1 | ADMINISTERING BENZYLIDENE RHODANINES WHICH ARE USEFUL AS AGENTS IN TREATING OR PREVENTING CONDITIONS ASSOCIATED WITH BETA-AMYLOID PEPTIDE IN A MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6046212-A | ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5747517-A | ALZHEIMER'S DISEASE; PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| EP-0677517-A1 | Treatment of Alzheimer's disease employing inhibitors of cathepsin D | ELI LILLY AND COMPANY (US) | 1995-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120076954-A1 | CYCLIC OLEFIN COMPOUND, PHOTOREACTIVE POLYMER, AND ALIGNMENT LAYER COMPRISING THE SAME | MYB, CDK14, CCNL2 | RAB9A 1323/4885ALOX5 266/4885ALDH1A1 4641/4885 |
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | HAVCR2, HDLBP, HSP90B1 | RAB9A 1566/4885ALOX5 4768/4885ALDH1A1 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.