Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | UTRN | P46939 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644084 | 0.83 | KMT2A (0.36) | — | |
| SCHEMBL8647859 | 0.83 | RXFP1 (0.39) | RXFP1PDE3BPDE3APLA2G2A | |
| SCHEMBL9700960 | 0.82 | MAPT (0.35) | RXFP1EGFRPLA2G2APRMT5WDR77 | |
| SCHEMBL9740990 | 0.82 | MAPT (0.35) | RXFP1EGFRPLA2G2APRMT5WDR77 | |
| SCHEMBL9699664 | 0.72 | MMP1 (0.41) | UTRN | |
| SCHEMBL8645097 | 0.72 | KMT2A (0.36) | — | |
| SCHEMBL9006020 | 0.70 | NPY5R (0.38) | EGFR | |
| SCHEMBL8644339 | 0.69 | RXFP1 (0.36) | RXFP1PRNPEGFRPDE3BPDE3A | |
| SCHEMBL9700956 | 0.69 | TSHR (0.37) | RXFP1 | |
| SCHEMBL8646944 | 0.68 | KDM4E (0.42) | RXFP1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710139-A | Heterocyclic compounds | ASTRA AB (SE) | 1998-01-20 | — | — | US | disclosed |
| EP-0736032-A1 | HETEROCYCLIC COMPOUNDS | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017410-A1 | HETEROCYCLIC COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-06-29 | — | — | WO | disclosed |