Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700960 | 1.00 | MAPT (0.35) | MAPTMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL9699664 | 0.86 | MMP1 (0.41) | ALDH1A1ERBB2 | |
| SCHEMBL9700956 | 0.83 | TSHR (0.37) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8644342 | 0.82 | RXFP1 (0.39) | EGFRPRMT5WDR77RXFP1PLA2G2A | |
| SCHEMBL9701697 | 0.81 | ERBB2 (0.44) | MAPTMEN1KMT2AKDM4EERBB2 | |
| SCHEMBL9700727 | 0.81 | PIK3CG (0.46) | MAPTMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL30932231 | 0.81 | PIK3CG (0.46) | MAPTMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL9163760 | 0.74 | TSHR (0.42) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9746062 | 0.73 | MMP1 (0.36) | — | |
| SCHEMBL9742893 | 0.72 | ALDH1A1 (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |